Oxidative Stress in Obesity and Metabolic Syndrome in Asian Indians
نویسندگان
چکیده
منابع مشابه
Association of Inflammatory and Oxidative Stress Markers with Metabolic Syndrome in Asian Indians in India
Metabolic syndrome (MetS) is a primary risk factor for cardiovascular disease and is associated with a proinflammatory state. Here, we assessed the contribution of inflammatory and oxidative stress markers towards prediction of MetS. A total of 2316 individuals were recruited in Phase I of the Indian Atherosclerosis Research Study (IARS). Modified ATPIII guidelines were used for classification ...
متن کاملInflammation and Oxidative Stress in Obesity, Metabolic Syndrome, and Diabetes
I do not think anybody even remotely connected with the field of diabetes, either as a researcher or as a health care provider, would have any serious objection to the concept that some degree of altered inflammatory activity or oxida-tive stress plays a serious role in multiple aspects of diabetes. Just to mention two of the best-known processes, a violent, acute inflammatory event leads to th...
متن کاملRole of oxidative stress in pathogenesis of metabolic syndrome
The metabolic syndrome (MS) recognized as a major cause of type 2 diabetes and cardiovascular diseases, has become one of the major public health challenges worldwide. The pathogenesis of the metabolic syndrome is multiple and still poorly understood. No single factor has yet been identified as an underlying causal factor. There is a growing belief, however, that obesity, specially visceral obe...
متن کاملRole of Vascular Oxidative Stress in Obesity and Metabolic Syndrome
Obesity is associated with vascular diseases that are often attributed to vascular oxidative stress. We tested the hypothesis that vascular oxidative stress could induce obesity. We previously developed mice that overexpress p22phox in vascular smooth muscle, tg(sm/p22phox), which have increased vascular ROS production. At baseline, tg(sm/p22phox) mice have a modest increase in body weight. Wit...
متن کاملObesity-associated genetic variants in young Asian Indians with the metabolic syndrome and myocardial infarction
OBJECTIVE Associations between obesity-related polymorphisms and the metabolic syndrome in 485 young ( ≤ 45 Years) Asian Indian patients with acute myocardial infarction (AMI), and 300 matched controls were assessed. METHODS Genetic variants included the adiponectin 45T→G and 276G→T, LEPR K109R and Q223R, MC4R-associated C→T and FTO A→T polymorphisms. RESULTS The metabolic syndrome, as defi...
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ژورنال
عنوان ژورنال: Journal of Medical Biochemistry
سال: 2011
ISSN: 1452-8266,1452-8258
DOI: 10.2478/v10011-011-0006-6